HMG-COA reductase inhibitors include-

Fluvastatin, Lovastatin, Pravastatin, Simvastatin

Refer - Lovastatin

Approved by FDA on December 31,1993

Approved by FDA on December 31,1993

Dosage: Initial - 20mg once daily at bed time Dose range- 20 to 40mg/day as a single dose in the evening.

1. May cause photosentivity (sensitivity to sunlight) . Avoid prolonged exposure to the sun and other ultraviolet light.

2. Use sunscreens and wear protective clothing until tolerance is determined

3. Promptly report unexplained muscle pain, tenderness or weakness, especially if accompanied by fever or malaise

4. Follow dietary recommendationsl

5. Take lovastatin with meals, fluvastatin and simvastatin may be taken without regrads to meals.

HMG-COA reductase inhibitors include-

Fluvastatin, Lovastatin, Pravastatin, Simvastatin

Refer - Lovastatin