ANTIPRESS
Imipramine 25mg/50mg/75mg f.c. tablets,
Strength | Rate | Packing Style |
---|---|---|
25mg f.c. | 9.00 | 10s f.c.tablets |
50mg f.c. | 17.00 | 10s f.c.tablets |
75mg f.c. | 21.00 | 10s f.c.tablets |
List of Related Indications:
- Depression
List Of Drugs:
- Imipramine - @ Tricyclic
Indication Type Description:
Drug Interaction
Indication
Adverse Reaction
Contra-Indications
Dosages/ Overdosage Etc
Other Information
Patient Information
Pharmacology/ Pharmacokinetics
Interaction with Food
Pregnancy and lactation
Drug Interaction:
Tricylic Compounds include-
Tertiary amines - Amitriptyline,Clomipramine,Doxepin,Imipramine,Trimipramine
Secondary amines - Amoxipine, Desipramine, Nortriptyline,Portriptyline
Refer - Amitriptyline
Drug interactions- summary
Imipramine +
MAOIs. - fatal reactions may occur in combination with MAOIs Adrenaline, noradrenaline and methylpenidate - Severe hypertension Guanithedine, betaanidine,debrisoquine and bretylin. - reverses hypotension effects
Methyldopa and clonidine. - interferes with hypertensive action
Anticonvulsants - Reduction in seizure thresold, anticonvulsant dose to be increased.
Levopdopa - Interferes with absorption of levadopa.
Tranquillisers - tranquillsers inhibit metabolism,
Oral contraceptives - Oral contraceptives reduce bioavailability,
Barbiturates - reduce plasma levels thereby reducing antidepressant effect.
Cimetidine - elevates serum impiramine concentrations and adverse effect
Alcohol - combination with alcohol causes drowsiness and impaired performance.
Imipramine with MAOIs. fatal reactions may occur in combination with MAOIs Adrenaline, noradrenaline and methylpenidate. Severe hypertension with Guanithedine, betaanidine,debrisoquine and bretylin. reverses hypotension effects Methyldopa and clonidine. interferes with hypertensive action
Anticonvulsants -Reduction in seizure thresold, anticonvulsant dose needs to be increased.
Levopdopa -Interferes with absorption of levadopa.
Tranquillisers -Major tranquillsers inhibit metabolism, Oral contraceptives Oral contraceptives reduce bioavailability,