Drug Interaction:
Thiazides and related diuretics include- Bendroflumethiazide, Benzthiazide, Chlorthiazide, Hydrochlorthiazide, Hydroflumethazide, Indapamide, Methyclothizide, Metolazone, Polythiazide, Quinethazone, Trichlormethiazide Refer Hydrochlorthiazide- Thiazide and related diuretics
Indication:
FIXED DOSE COMBINATIONS APPROVED BY DCG(I)
FROM JANUARY 1961 TILL NOVEMBER 2014
Name of Drug Indication Date of Approval
Hydroflumethizide 25mg/50mg+ March 1971
Rauwalflia 50mg/50mg tablets
Edema, hypertension.
Thiazides and related diuretics include- Bendroflumethiazide, Benzthiazide, Chlorthiazide, Hydrochlorthiazide, Hydroflumethazide, Indapamide, Methyclothizide, Metolazone, Polythiazide, Quinethazone, Trichlormethiazide Refer Hydrochlorthiazide- Thiazide and related diuretics
Adverse Reaction:
Refer Hydrochlorthiazide
Contra-Indications:
Refer Hydrochlorthiazide
Dosages/ Overdosage Etc:
Indication
Edema, hypertension Dosage: Edema- initial 50mg once or twice a day.
Maintenance- 25mg to 200mg daily, administer in divided doses when dosages exceeds 100mg daily Hypertension- initial 50mg twice daily.
Maintenance- 50 to 100mg/day. Do not exceed 200mg/day
Patient Information:
Thiazide diuretics
1. May cause GI upset, may be taken with food
2. Drug will initially increase urination which should subside after a few weeks, take early during the day or as directed
3. Notify physician, if muscle pain,weakneess or cramps, nausea, vomiting, restlessness, excess thirsr, tiredness, drowsiness, increased heart rate or pulse, diarrhea, or dizziness occurs
4. May cause photosensitivity (sensitivity to sunlight). Avoid prologed exposure to the sun and other ultraviolet light. Use sunscreens and wear protective clothing until tolerance is determined
5. May increase blood sugar levels in diabetes
6. Do not drink alcohol or take other medications without physicians approval, this includes nonprescription medicines for appetite control, asthma, colds, cough,hay fever or sinus
7. Do not interrupt , discontinue or adjust the dose, even if feeling well. Follow physicians instruction regarding missed dose.
Pharmacology/ Pharmacokinetics:
Thiazides and related diuretics include- Bendroflumethiazide, Benzthiazide, Chlorthiazide, Hydrochlorthiazide, Hydroflumethazide, Indapamide, Methyclothizide, Metolazone, Polythiazide, Quinethazone, Trichlormethiazide Refer Hydrochlorthiazide- Thiazide and related diuretics
Pregnancy and lactation:
Refer Hydrochlorthiazide
Manufacturer Details