Drug Information

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Chromium - @ - Trace metals

Drug Name:
Chromium - @ - Trace metals

List Of Brands:

CHROMIUM *

Indication Type Description:

Indication

Dosages/ Overdosage Etc

Patient Information

Pharmacology/ Pharmacokinetics

Indication:

Supplement to IV solution given for TPN

Dosages/ Overdosage Etc:

Indication-

Supplement to IV solution given for TPN

Dosage:

Adults- 10 to 15mcg/day Metabolically stable adults- 20mcg/day

Children- 0.14 to 0.2mcg/kg/day Chromium Picolinate Recommended daily dose is 200- 1000mcg

Overdosage- Nausea, vomiting, GI ulcers, renal/hepatic damage, convulsions, coma

Patient Information:

Chromium supplements- Systemic

1.Allergies-

Tell your doctor if you are have ever had any unusual or allergic reaction to

chromium. Also tell your healthcare care professional if you are allergic to

any other substances such as foods. preservatives or dyes.

2.Pregnancy-

It is especially important that you are receiving enough vitamins and minerals

when you become pregnant and that you continue to receive enough vitamins

and minerals when you become pregnant and that you continue to get the right

amount of vitamins and minerals throughout your pregnancy .

The healthy growth and development of the fetus depend on a steady supply

of nutrients from the mother. However, large amounts of dietary supplement

during pregnancy may be harmful to the mother and/or fetus and should be

avoided

3. Breast-feeding-

It is especially important that you receive the right amount of vitamins and

minerals so that your baby will also get the vitamins and minerals needed

to grow properly. However, taking large amounts of dietary supplement

may be harmful to the mother and/or baby and should be avoided

4.Children-

Problems in children have not been reported with intake of normal daily

recommended amounts

5.Older adults-

Problems in older adults have not been reported with intake of normal daily

recommended amounts

6. Other medicines-

Although certain medicines should not be used together at all, in other cases two

different medicines may be used together even if an interaction might occur.

In such cases your doctor may want to change the dose, or other precautions

may be necessary.

Tell your doctor if you are using any other prescription or non-prescription

(Over-the counter) OTC medicine.

7. Other medical problems-

The presence of other medical problems may affect the use of chromium.

Make sure you tell your doctor if you have any other medical problems

especially-

Diabetes mellitus (sugar diabetes) - taking chromium supplements when

you have a chromium deficiency may cause a change in the amount

of insulin you need.

Pharmacology/ Pharmacokinetics:

Pharmacology:

The human body secretes the hormone insulin. The primary function of insulin is to convert glucose into glycogen. Chromium is considered an essential trace nutrient. Cr binding protein a naturally occuring oligopeptide, low molecular weight chromium binding substance(LMWCr) has been found to activate insulin receptor kinase activity up to 7 fold. This activation may lead to increased insulin sensitivity

Pharmacokinetics:

After oral administration of chromium picolinate supplement at 40mcg Cr/day for 3 days to male and female volunteers, the mean percentage of Cr absorbed was 2.8% with a range of 1.5 -5.2%. Half of the dose is retained in the liver. It is slowly excreted from cells and tissues and therefore, increased absorption of Cr may lead to accumulation of chromium.

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