46/15.  Aflibercept- (BNF)- (EYELEA) -Bayer) -Ocular diagnostic agent

Indications-

Cautions-                 monirtor intra-ocular ptessure following injection- patients at risk                                   of  retinal pigment epithelial tearsk of 

Contra-indications-     ocular or periocular infection, sevrere intra-ocular                                                             inflammation, patients at risk of retinal pigment epithelial                                            tear

Pregnancy-                manufactutrer advices avoid unless potential benefit                                                    outweighs risk and recommend women use effective                                                   contraception during the first 3 months after trreatment

Breast feeding-        manufacturre advices avoid

Side  effects-          also conjuntivial  haemorrhage, vitrous haemorrhage, cornial                                       erosion,eye pain,retinal pigment epithelium tear, retinal                                              degenerNation

Dose-                     Neovacular wet age related mcular degeneration by intravitreal                                     injection- adult- ovr 18 years 2mg into the affected eye once a                                    momth for 3 months then every 2 months threafteredema

                          Macular edma deconary to central retinal ven occlusion b                                            intavitreal injection adult over 18 yrs 2mg every 2 months into the                               affected eye once amonth