Paracetamol + Chlormezanone/Chlorzoxazone
Drug Name:
Paracetamol + Chlormezanone/Chlorzoxazone
List Of Brands:
Indication Type Description:
Drug Interaction:
Chlormezanone/Chlorzoxazone- Alcohol or other CNS depressants ( eg. barbiturates, narcotics ) possible additive CNS effects may occur when taken with chlormezanone
Indication:
Painful muscle spasm associated with musculoskeletal conditions
Adverse Reaction:
Chlormezanone/Chlorzoxazone- Drowsiness, weakness, nausea, dizziness, skin rash, flushing of skin, lightheasded ness, headache, Confusion, excitement, depression, Dryness of the mouth, GI disturabances, Cholestatic jaundice, Jaundice may occur,
Liver damage reported orange or reddish -purple urine Anaphyloid reactions, Angioedema, fatal hepatocellular toxicity Eryherma mutiforme, Steven-Johnson syndrome and toxic epidrmal necrolysis
Contra-Indications:
Chormezanone/Chloroxazone- Hypersensitivity, porphyria, liver disease, Lactation Special precautions- Impired renal/liver function, Pregnancy and lactation, Known allergies, Tasks requiring mental alertness may be impaired Monitor liver function
Dosages/ Overdosage Etc:
Painful muscle spasm associated with musculoskeletal conditions
Dosage-
Chlorzoxazone- Adult- initially 500mg 3-4 times daily may subsequently reduce to 250mg 3-4 times daily Max- 750mg 3-4 times daily
Patient Information:
This drug may impair the mental or physical abilities for th performance of potentiall hazardous tasks such as driving or operating machinery Avoid alcohol while taking this drug Notify physician if skin rash, sore throat or fever occurs.
Pregnancy and lactation:
Safety for use during pregnancy and lactation has not been established. Use only when clearly needed and when the potential benefits outweigh the potential hazards to the fetus
