As per US FDA guidelines as per USPDA 1997

It is the intention to bring out the salient features. Hence relevent details as prescribed by US FDA guidelines as per USPDA 1997  are brought out clearly in the following chapters. 

Descriptons are detailed only to the Group Head and the indiviual items can be seen by visiting the Web Site 

NSAIDs include-

Propionic acid- Fenoprofen, Flurbiprofen, Ibuprofen, Ketoprofen, Naproxen, Naproxen Sodium, Oxaprozin
Acetic acids-  Diclofenac sodium, Etodolac, Indomethicin, Ketorolac, Nabumetone, Sulindac, Tolmetin
Fenamates (anthralic acids) - Meclofenamate, Mefenamic acxid
Oxicams- Piroxicam
 

Refer- Ibuprofen

1. Side effects of NSAIDs  can cause discomfort and rarely, more serious side effects such as  GI bleeding which may result in hospitalisation and even fatalites. NSAIDs  are often  essential    in manangement of arthiritis and have a major role  in treating pain but they also may  be commonly employed for less serious conditions. Appraise potential patients of potential risks. 

2. Avoid aspirin and alcoholic beverages while taking medication.

3. If GI upset occurs, take with food, milk or antacids. For GI upset with tolmetin, use antacids other  than sodium bicabonate, bioavailbility is affected by food and milk.
 If GI symptoms persist, consult physician

4. May cause cause drowsiness, dizziness, or blurred vision, patients should observe   caution while driving or peforming other tasks  requiring alertness 

5. Notify physician if skin rash, itching, visual disturbances, weight gain, edema, black stools, or persistent headache occurs.

6. Mefanamic acid and meclofenamate - if rash , diarrhea or other digestive problems occur,  discontinue use and consult a physician

7. Ibuprofen ( otc use ) - do not take for > 3 days for fever or 10 days for pain, If these symptoms  persist, worsen or if new symptoms develop, contact a physician  

8. Allergies-  Tell your doctor if you have ever had any unusual or allergic reaction to NSAID
    or any other  medicines e.g.   Aspirin or other salicylates
   

9. Diet- Make sure your doctor knows if you are on any special diet, such as low-sodium
   or low sugar. Some of these medicines contain certain sodium or sugar.

10. Pregnancy- If you are pregnant do not take any of these medicines including
   non-prescription OTC drugs- ibuprofen or naproxen without dscussing its use with your   doctor.

11. Breast feeding-    Indomethicin- passes into breast milk and has been reported to cause unwanted effects in nursing  babies. Meclofenamate- use not recommended.     

12. Children-
      Ibuprofen- ibuprofen has been tested in children 6 months of age and older

     Not shown  to cause any different side effects than they do in adults  Indomethicin and  

    Tolmetin- indomethicin and tolmetin and have cause any different  effects than they do in  adults
      Naproxen- studies in children have shown that skin rash may be more likely  to occur.
      Oxaprozin- oxaprozin has been used in children with arthiritis.
       Phenylbutazone- use of phenylbutazone in children up to 15 years of age not  recommened.
      Other anti-inflammatory drugs- no specific information on use in children available.

13. Elderly- Certain side effects such as confusion, swelling of the face, feet or lower legs
      or sudden  decrease in the amount of urine may occur in elderly patients.
      With phenylbutazone ,blood problems  may also occur in the elderly.

 14. Other medicines-  Let your doctor know if you are taking any other medicines                 .e,g.  Anticoagulants or
       Cefamandole or  Cefoperazone, Heparin - change of bleeding may be                                   increased        
15. Other medical problems- Make sure you tell your doctor, if you have any other                    medical    problems-  Alcohol abuse or Bleeding problems or Colitis ,Crohns                     disease, diverticulitis,,stomach ulcer, or other stomach or intestinal problems -                     chance of side effects may  be increased
                              
 16 Missed dose-  If you are taking the medicine regularly and you miss a dose, take it          as  soon as possible.  However ifis time for the next dose, skip the missed dose and         go  back  to your regular  dosing schedule.  Do not double doses.

 17. Storage- Keep the medicines our of reach of children
          Store the medicines away heat and direct light. Do not store tablets  or capsules
          in the bath room, in damp places near the kitchen sink .
          Heat and moisture will cause the medicines to break down             
          Do not store out dated medicines  or medicines no longer needed.
          Make sure that  all discarded medicines are kept out of reach of children