Care should be excercised when domperidone is administered in combination with MAOI inhibitors

Dyspepsia Gastro-oesophageal reflux

Pantoprazole-

Diarrheoa, dizziness, prurotus, skin rashes GIT infections,anaphylaxis, angioedema, chest pain Dyspnoea, erythema multiforme, gastroenteritis, Hyperglycemia, infection Inj site reactions, jaundice, optic neuropathy, Anterior ischemia, pancreatitis, Pancreatitis, speech disorder

Domperidone-

Headache, insomnia, nervousness, dizziness, Thirst, lethargy, instability GI disturbances, hot flushes, mastalgia, Galactorrhea, gynocomastia, Menstrusal irregularities, Rash, pruritus, urticaria, stomatitis, Conjuntivitis, Urinary frequency, dysuria, oedema

Pantoprazole-

Hepatic impairment, hypersensitivity,

Domperidone History of hypersentivity to dimenhydrinate or related compounds GI haemorrhage, obstruction and perforation ,or after surgery

Pregnancy

Special precautions-

Lactation- Pantoprazole- Not recommended in child < 12 years Long term therapy may lead to bascterial overgrowth in the GI tract

Domperidone- Incease serum prolactin level resulting in galactorrhea in females and gynocomastia in males Hypersentivity crisis in patients with phaechromocytoma

Indication-

Dyspepsia Gastro-oesophageal reflux

Dosage

1 tablet /capsule once daily

Contraindicated for use during pregnancy and lactation