Alendronate Sodium - Bisphosphonates- (FDC List) (Sep 1995)

Drug Name:
Alendronate Sodium - Bisphosphonates- (FDC List) (Sep 1995)

List Of Brands:

Indication Type Description:

Drug Interaction

Indication

Adverse Reaction

Contra-Indications

Dosages/ Overdosage Etc

Other Information

Patient Information

Pharmacology/ Pharmacokinetics

Interaction with Food

Pregnancy and lactation

   

Drug Interaction:

Bisphonates include-

Alendronate, Etidronate, Pamidronate Refer Alendronate

Interacting drugs- summary

+ Alendronate

Ranitidine/ +

 IV ranitidine doubled alendronate bioavailability. The clinical significance unknown 

Calcium Supplement +

 product containing calcium and other multi-valent cations interfere with  alendronate and etidronate absorptin

Alendronate + Apirin

Risk of GI adverse effects associated with aspirin increased with alendroate doses > 10mg/day

Calcium supplements, iron and antacids may hinder absorption of alendronate. Avoid concomittant use with aspirin or NSAIDs for they may increase the incidence of adverse effects